This paper studies socioeconomic disparities in Mexico based on sexual orientation and gender identity using data from a nationally representative survey collected between 2021 and 2022 (N44,189). It finds pronounced levels of self-reported discrimination and rejection among LGBTQ individuals throughout their lives. It also estimates that these groups rates of labor force participation and unemployment diverge from those of their heterosexual and cisgender counterparts. Additionally, a heterogeneity analysis provides novel insights into nuanced disparities within LGBTQ groups.